Why Should Go For Novel Coronavirus Neutralizing Antibody Test
There are several testing methods have been developed to track and contain the pandemic. From all these types of issues, it is quite essential to keep in mind that, everything will be rightly purposed with the help of high quality novel coronavirus neutralizing antibody test and it will be rightly conducted by the best possible way to deliver all these type of issues on right time. This is the main reason, you need to keep in mind regarding the best tactical way to deliver the outstanding result that would make something crucial with the help of perfect and simple compulsion.
Although molecular detection techniques, such as the
polymerase chain reaction (PCR) and next-generation sequencing, have played an
important role in acute diagnosis and monitoring of genetic changes of the
virus, an urgent need exists for a reliable and versatile serological or
antibody test. Such a test is needed for retrospective contact tracing,
investigation of the asymptomatic infection rate, accurate determination of the
case fatality rate, and assessment of herd immunity and humeral protective
immunity in recovered patients and recipients of vaccine candidates, and in the
search for the natural reservoir and intermediate host(s)6. Research laboratories and pharmaceutical companies
are racing to produce antibody tests that can detect COVID-19 infection with sufficient
specificity and sensitivity6. There are two types of antibody test one can aim
for. With IVD reagents these things will be also possible
to deliver the best result.
The first type is the conventional virus neutralization test
, which detects neutralizing antibodies in a patient’s blood. The requires
handling live SARS-CoV-2 in a specialized bio safety level 3 containment
facility and is tedious and time-consuming, taking 2–4 days to complete. The
pseudo virus-based VNT on the other hand, can be performed in a BSL2
laboratory, but still requires the use of live viruses and cells7,8. All other assays, such as enzyme-linked immune sorbent
assay (ELISA) and lateral flow assay rapid tests, represent the second assay
type, which detects total binding antibodies and is unable to differentiate
between two types of things.
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